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But, nasal steroid sprays such as fluticasone propionate (Flonase), mometasone furoate (Nasonex), and triamcinolone acetonide (Nasacort) are considered by experts the best, first option for seasonal allergies.

Both Flonase and Nasacort are recently available without a prescription.

If you and your doctor have decided an antihistamine is appropriate for your allergy symptoms, we have selected the following as Consumer Reports Best Buy Drugs based on dosing convenience, cost, effectiveness and safety: Those are all low-cost generics available in various formulations (liquid, tablet, chewables, dissolvables) without a prescription.

Some people may respond well to one antihistamine while getting no benefit from another.

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While the second-generation antihistamines can help relieve allergy symptoms, they usually don’t clear them up entirely.

In people who have allergies, the body’s immune system overreacts when exposed to otherwise harmless substances—animal dander, dust mites, mold spores, or pollen—by releasing excessive amounts histamine.

That chemical is a part of the body’s natural defense mechanisms, and it works in part by widening blood vessels, which also causes congestion and sneezing. About 17.6 million adults and 6.6 million children in the U. were diagnosed with allergies in 2012, according to the Centers for Disease Control and Prevention.

Several types of allergy treatments are available—allergy shots, antihistamines (pills, eye drops, and nasal sprays), cromolyn, leukotriene blockers, and nasal steroid sprays.

This report focuses on second-generation antihistamine pills and nasal sprays, such as Allegra, Clarinex, Claritin, Xyzal, and Zyrtec.